About Pitt-PRAM
Female reproductive aging is the earliest manifestation of aging in humans, with fertility declining well before menopause. Menopause marks the definitive end of reproductive potential and the onset of increased risk for multiple age-related, chronic diseases. Emerging evidence links reproductive disorders, from infertility to widespread gynecological conditions with elevated risks of premature morbidity and mortality. Indeed, it is increasingly evident that even normal reproductive transitions such as puberty, pregnancy, and menopause, act as physiological inflection points that shape long-term systemic health. Yet, fertility continues to be viewed primarily through the prism of procreation, with limited knowledge of the underlying biological mechanisms and scarce clinical focus on its broader health implications.
Recent discoveries elucidating the genetic basis of reproductive traits combined with advances in our understanding of fundamental aging mechanisms offer a compelling framework to address these persistent knowledge gaps with far-reaching public-health consequences.
Our Mission
Pitt-PRAM supports research, education, and mentorship in reproductive aging by building a strong, connected pipeline from undergraduate students to junior faculty. Through early recruitment, innovative training, and long-term mentoring, we help develop the next generation of leaders in reproductive health and aging science.
Our Vision
We envision the University of Pittsburgh as a world leader in reproductive aging research and training, where scientists at every stage are empowered to collaborate and drive discovery. Through Pitt-PRAM’s growing pipeline, we support a diverse community of researchers working to advance reproductive health and improve lives across the lifespan.